AMR Forschung - Miscellaneous

Struktur und Funktion

Projekte

LAPIN: Leads against Gram-negative Pathogens: Identifizierung von neuen Leitmolekülen zur Inaktivierung der essenziellen Na+-Pumpe in gram-negativen, multiresistenten Erregern (Julia Fritz-Steuber; gefördert von der Else Kröner Fresenius Stiftung, 01.05.2019 - 30.04.2021)

Publikationen

• Jarick, Marcel; Bertsche, Ute; Stahl, Mark; Schultz, Daniel; Methling, Karen; Lalk, Michael et al. (2018): The serine/threonine kinase Stk and the phosphatase Stp regulate cell wall synthesis in Staphylococcus aureus. In: Scientific Reports 8 (1). DOI: 10.1038/s41598-018-32109-7.
• Toulouse C, Metesch K, Pfannstiel J, Steuber J. (2018) Metabolic reprogramming of Vibrio cholerae impaired in respiratory NADH oxidation is accompanied with increased copper sensitivity. J Bacteriol. 2018 May 7. pii: JB.00761-17. doi: 10.1128/JB.00761-17. [Epub ahead of print]
• Yue M, Han X, Masi LD, Zhu C, Ma X, Zhang J, Wu R, Schmieder R, Kaushik RS, Fraser GP, Zhao S, McDermott PF, Weill F-X, Mainil JG, Arze C, Fricke WF, et al. (2015): Allelic variation contributes to bacterial host specificity. Nat Commun 2015;6:8754. doi:10.1038/ncomms9754.
• Fricke WF, Rasko DA (2013): Bacterial genome sequencing in the clinic. Bioinformatic challenges and solutions. Nat Rev Genet. 15(1):49-55.
  Domingues S, Harms K, Fricke WF, Johnsen PJ, da Silva GJ, Nielsen KM (2012): Natural transformation facilitates transfer of transposons, integrons and gene cassettes between bacterial species. PLoS Pathog 8:e1002837. doi:10.1371/journal.ppat.1002837
• Angiuoli SV, Matalka M, Gussman A, Galens K, Vangala M, Riley DR, Arze C, White JR, White O, Fricke WF (2011): CloVR: a virtual machine for automated and portable sequence analysis from the desktop using cloud computing. BMC Bioinformatics 12:356. doi:10.1186/1471-2105-12-356.
• Fricke WF, Mammel MK, McDermott PF, Tartera C, White DG, LeClerc JE, et al. (2011): Comparative genomics of 28 Salmonella enterica isolates: evidence for CRISPR-mediated adaptive sublineage evolution. J Bacteriol 193:3556–68. doi:10.1128/JB.00297-11.
• Fricke WF, Welch TJ, McDermott PF, Mammel MK, LeClerc JE, White DG, Cebula TA, Ravel J (2009): Comparative Genomics of the IncA/C Multidrug Resistance Plasmid Family. J Bacteriol. 191(15):4750-7.