Hohenheim Research Center for One Health Sciences

Anwendung im Lebensmittelsektor

Aktuelle Projekte:

Erhöhte Phagensicherheit in Molkereien durch hochspezifische molekulare Phagen-Nachweissysteme und eine orthogonale Prozessstrategie zur Phagenreduktion in Molke

Publikationen

 

  • Ergin, Firuze; Atamer, Zeynep; Comak Göcer, Emine Mine; Demir, Muammer; Hinrichs, Jörg; Kucukcetin, Ahmet (2020): Optimization of Salmonella bacteriophage microencapsulation in alginate-caseinate formulation using vibrational nozzle technique. In: Food Hydrocolloids, S. 106456. DOI: 10.1016/j.foodhyd.2020.106456.
  • Eichhorn I, Heidemanns K, Ulrich RG, Schmidt H, Semmler T, Fruth A, Bethe A, Goulding D, Pickard D, Karch H, Wieler LH.(2018) Lysogenic conversion of atypical enteropathogenic Escherichia coli (aEPEC) from human, murine, and bovine origin with bacteriophage Φ3538 Δstx2::cat proves their enterohemorrhagic E. coli (EHEC) progeny. Int J Med Microbiol. 2018 Jun 19. pii: S1438-4221(18)30207-8. doi: 10.1016/j.ijmm.2018.06.005. [Epub ahead of print]
  • Brinks, Erik; Wagner, Natalia; Neve, Horst; Samtlebe, Meike; Hinrichs, Jörg; Franz, Charles M.A.P.; Heller, Knut J. (2018): Detection of Lactococcus lactis phage P680, a heat resistant member of the 936 group of phages, by loop-mediated isothermal amplification (LAMP). In: International Dairy Journal 82, S. 1–3. DOI: 10.1016/j.idairyj.2018.02.007.
  • M Samtlebe, S Denis, S Chalancon, Z Atamera, N Wagner, H Neve, C Franz, H Schmidt, S Blanquet-Diot, J Hinrichs (2018). Bacteriophages as modulator for the human gut microbiota: Release from dairy food systems and survival in a dynamic human gastrointestinal model. LWT. In Press 10.1016/j.lwt.2018.01.033.
  • Denyes JM, Dunne M, Steiner S, Mittelviefhaus M, Weiss A, Schmidt H, Klumpp J, Loessner MJ (2017): Modified Bacteriophage S16 Long Tail Fiber Proteins for Rapid and Specific Immobilization and Detection of Salmonella Cells. Applied and environmental microbiology 83 (12). DOI: 10.1128/AEM.00277-17.
  • Samtlebe, M, Wagner, N, Brinks, E, Neve, H, Heller, KJ, Hinrichs, J, Atamer, Z (2017): Production of phage free cheese whey. Design of a tubular laboratory membrane filtration system and assessment of a feasibility study. In: International Dairy Journal 71, 17–23. DOI: 10.1016/j.idairyj.2017.02.006.
  • Samtlebe, M, Wagner, N, Brinks, E, Neve, H, Heller, KJ, Hinrichs, J, Atamer, Z  (2017): Reduction of Lactococcus lactis phage contamination in whey by means of membrane filtration. Impact of phage morphology and of bacterial host cells functioning as “phage fishing tool”. In: International Dairy Journal 68, 88–94. DOI: 10.1016/j.idairyj.2017.01.006.
  • Wagner N, Brinks E, Samtlebe M, Hinrichs J, Atamer Z, Kot W et al. (2017): Whey powders are a rich source and excellent storage matrix for dairy bacteriophages. International journal of food microbiology 241, 308–317. DOI: 10.1016/j.ijfoodmicro.2016.10.037.
  • Wagner, N, Samtlebe, M, Franz, C, M.A.P.; Neve, H, Heller, KJ.; Hinrichs, J, Atamer, Z (2017): Dairy bacteriophages isolated from whey powder. Thermal inactivation and kinetic characterisation. In: International Dairy Journal 68, 95–104. DOI: 10.1016/j.idairyj.2016.12.017.
  • Samtlebe M (2016): Bakteriophagen in Molke: Möglichkeiten der Reduktion für eine erhöhte Prozesssicherheit. In: 16. Fachsymposium Lebensmittelmikrobiologie. Stuttgart-Hohenheim, S. 65-66.
  • Samtlebe M, Ergin F, Wagner N, Neve H, Küçükçetin A, Franz CMAP et al. (2016): Carrier systems for bacteriophages to supplement food systems. Encapsulation and controlled release to modulate the human gut microbiota. LWT – Food Science and Technology 68, 334–340. DOI: 10.1016/j.lwt.2015.12.039.
  • Samtlebe M, Wagner N, Neve H, Heller KJ, Hinrichs J, Atamer Z (2015): Application of a membrane technology to remove bacteriophages from whey. International Dairy Journal 48, 38–45. DOI: 10.1016/j.idairyj.2014.12.004.
  • Jaglic Z, Desvaux M, Weiss A, Nesse LL, Meyer RL, Demnerova K et al. (2014): Surface adhesins and exopolymers of selected foodborne pathogens. Microbiology 160 (Pt 12), 2561–2582. DOI: 10.1099/mic.0.075887-0.
  • Muniesa M, Schmidt H (2014): Shiga toxin-encoding phages: multifunctional gene ferries. In: Pathogenic Escherichia coli. - Norfolk : Caister Acad. Pr., 57-77.
  • Nubling S, Eisele T, Stober H, Funk J, Polzin S, Fischer L, Schmidt H (2014): Bacteriophage 933W encodes a functional esterase downstream of the Shiga toxin 2a operon. International journal of medical microbiology 304 (3-4), 269–274. DOI: 10.1016/j.ijmm.2013.10.008.
  • Ali Y, Kot W, Atamer Z, Hinrichs J, Vogensen FK, Heller KJ, Neve H (2013): Classification of lytic bacteriophages attacking dairy Leuconostoc starter strains. Applied and environmental microbiology 79 (12), 3628–3636. DOI: 10.1128/AEM.00076-13.
  • Atamer Z, Samtlebe M, Neve H, Heller KJ, Hinrichs J (2013): Review: elimination of bacteriophages in whey and whey products. Frontiers in microbiology 4, 191. DOI: 10.3389/fmicb.2013.00191.
  • Capra ML, Neve H, Sorati PC, Atamer Z, Hinrichs J, Heller KJ, Quiberoni A (2013): Extreme thermal resistance of phages isolated from dairy samples. Updating traditional phage detection methodologies. International Dairy Journal 30 (2), 59–63. DOI: 10.1016/j.idairyj.2012.11.009.
  • Atamer Z, Ali Y, Neve H, Heller KJ, Hinrichs J (2011): Thermal resistance of bacteriophages attacking flavour-producing dairy Leuconostoc starter cultures. International Dairy Journal 21 (5), 327–334. DOI: 10.1016/j.idairyj.2010.11.005.
  • Atamer Z, Hinrichs J (2010): Thermal inactivation of the heat-resistant Lactococcus lactis bacteriophage P680 in modern cheese processing. International Dairy Journal 20 (3), 163–168. DOI:10.1016/j.idairyj.2009.09.006.
  • Atamer Z, Dietrich J, Müller-Merbach M, Neve H, Heller KJ, Hinrichs J (2009): Screening for and characterization of Lactococcus lactis bacteriophages with high thermal resistance. International Dairy Journal 19 (4), 228–235. DOI: 10.1016/j.idairyj.2008.10.012.
  • Imamovic L, Jofre J, Schmidt H, Serra-Moreno R, Muniesa M (2009): Phage-mediated Shiga toxin 2 gene transfer in food and water. Applied and environmental microbiology 75 (6), 1764–1768. DOI: 10.1128/AEM.02273-08.
  • Loukiadis E, Nobe R, Herold S, Tramuta C, Ogura Y, Ooka T et al. (2008): Distribution, functional expression, and genetic organization of Cif, a phage-encoded type III-secreted effector from enteropathogenic and enterohemorrhagic Escherichia coli. Journal of bacteriology 190 (1), 275–285. DOI: 10.1128/JB.00844-07.
  • Muller-Merbach M, Kohler K, Hinrichs J (2007): Environmental factors for phage-induced fermentation problems: replication and adsorption of the Lactococcus lactis phage P008 as influenced by temperature and pH. Food microbiology 24 (7-8), 695–702. DOI: 10.1016/j.fm.2007.04.003.